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Glutathione peroxidase mimic inhibits the formation of estrogen-induced reactive oxygen species. Pretreatment with the glutathione peroxidase mimic ebselen showed a significant reduction of E2-induced oxidants in endothelial cells. Data from three independent experiments are presented as ROS production with controls set at 100% (± SD). Values that are significantly different from E2 treatment alone (P < 0.05) are indicated with an asterisk (*).
