Table 3.
Logistic Regression Model for Prediction of Mood Disturbance
| Raw Proportion
|
||||||
|---|---|---|---|---|---|---|
| Treatment Variable | No. of Patients | % | Model Risk (%) | Model Relative Odds | 95% CI | P |
| Age at diagnosis, years | ||||||
| Older than 12.5 | 35/223 | 15.7 | 18.3 | 1.0 | ||
| Younger than 12.5 | 98/332 | 29.5 | 45.2 | 3.7 | 2.0 to 6.6 | < .001 |
| Treatment | ||||||
| No-low | 32/131 | 24.1 | 36.3 | 1.0 | ||
| High MTX | 38/187 | 20.3 | 19.6 | 0.4 | 0.2 to 1.2 | .11 |
| High CRT | 51/179 | 28.5 | 20.1 | 0.4 | 0.2 to 1.2 | .10 |
| High both | 12/58 | 20.7 | 49.4 | 1.7 | 0.4 to 6.8 | .45 |
| Treatment X, highest education | ||||||
| Some college | ||||||
| No-low | 22/73 | 30.1 | 28.9 | 1.0 | ||
| High MTX | 21/105 | 20.0 | 20.7 | 0.6 | 0.3 to 1.4 | .26 |
| High CRT | 14/70 | 20.0 | 13.2 | 0.4 | 0.2 to 0.9 | .02 |
| High both | 6/28 | 21.4 | 21.1 | 0.7 | 0.2 to 2.0 | .46 |
| High school graduate | ||||||
| No-low | 7/50 | 14.0 | 18.4 | 1.0 | ||
| High MTX | 15/68 | 22.0 | 37.3 | 2.6 | 0.9 to 7.9 | .09 |
| High CRT | 34/98 | 34.7 | 35.7 | 2.5 | 0.9 to 6.5 | .07 |
| High both | 5/28 | 17.9 | 29.2 | 1.8 | 0.5 to 7.2 | .39 |
| Dropout | ||||||
| No-low | 3/8 | 37.5 | 67.0 | 1.0 | ||
| High MTX | 2/14 | 14.3 | 8.5 | 0.1 | 0.0 to 0.8 | .03 |
| High CRT | 3/11 | 27.3 | 15.7 | 0.1 | 0.0 to 1.3 | .07 |
| High both | 1/2 | 50.0 | 89.3 | 4.1 | 0.1 to 171 | .47 |
| Demographics | ||||||
| Highest education | ||||||
| Some college | 63/276 | 22.8 | 20.4 | 1.0 | ||
| High school graduate | 61/244 | 25.0 | 29.5 | 1.63 | 0.6 to 4.8 | .37 |
| Dropout | 9/35 | 25.7 | 42.4 | 2.87 | 0.6 to 13.1 | .17 |
| Ethnicity | ||||||
| White | 110/448 | 24.6 | 24.8 | 1.00 | ||
| Minority | 23/67 | 34.3 | 35.8 | 1.7 | 0.1 to 3.2 | .01 |
| Sex X, ethnicity | ||||||
| White | ||||||
| Male | 45/244 | 18.4 | 15.9 | 1.00 | ||
| Female | 65/244 | 26.6 | 36.7 | 3.1 | 1.4 to 6.8 | .006 |
| Nonwhite | ||||||
| Male | 13/34 | 38.2 | 41.6 | 3.8 | 1.6 to 9.2 | .004 |
| Female | 10/33 | 30.3 | 30.3 | 2.3 | 0.7 to 7.2 | .15 |
| Sex X, special education | ||||||
| Male | ||||||
| No special education | 51/253 | 20.2 | 26.3 | 1.00 | ||
| Yes special education | 7/25 | 28.0 | 27.4 | 1.1 | 0.3 to 4.1 | .94 |
| Female | ||||||
| No special education | 61/253 | 24.1 | 17.0 | 1.00 | ||
| Yes special education | 14/24 | 58.3 | 55.2 | 6.0 | 1.8 to 20.0 | .003 |
| Special education X, highest education | ||||||
| Some college | ||||||
| No special education | 61/266 | 22.9 | 35.8 | 1.0 | ||
| Yes special education | 2/10 | 20.0 | 10.5 | 0.2 | 0.0 to 1.4 | .11 |
| High school graduate | ||||||
| No special education | 48/216 | 22.2 | 25.1 | 1.00 | ||
| Yes special education | 13/28 | 46.4 | 34.4 | 1.6 | 0.6 to 4.0 | .35 |
| Dropout | ||||||
| No special education | 3/24 | 12.5 | 9.6 | 1.00 | ||
| Yes special education | 6/11 | 54.5 | 83.6 | 48.2 | 5.1 to 457 | < .001 |
| Perceptions | ||||||
| Has cancer limited your ability to work? | ||||||
| No | 96/466 | 20.6 | 19.2 | 1.0 | ||
| Yes | 37/89 | 40.4 | 43.6 | 3.3 | 1.8 to 5.8 | < .001 |
| Self-reported health | ||||||
| Excellent | 38/226 | 16.8 | 17.7 | 1.00 | ||
| Good | 72/284 | 25.4 | 26.4 | 1.71 | 0 to 2.7 | .04 |
| Poor | 23/45 | 51.1 | 50.6 | 4.7 | 2.2 to 10.5 | < .001 |
NOTE. Model retains nonsignificant covariates: age at interview, relapse (yes or no), and mother’s highest level of education.
Abbreviations: MTX, methotrexate; CRT, CNS irradiation.