Table 1.
Clinical and Tumor Characteristics in the Three Studies for Each Regimen and ER status. Denominators are numbers of patients within ER-status, study/regimen group. Numerators are the numbers of patients in that group having the characteristic.
| Characteristic | |||||||
|---|---|---|---|---|---|---|---|
| Postmenopausal
|
Tumor size, ≥ 2 cm
|
Positive nodes, ≥ 4
|
|||||
| Study | Regimen | ER- negative | ER- positive | ER- negative | ER- positive | ER- negative | ER- positive |
| 8541 | Low dose | 102/189 (54) | 128/154 (83) | 123/187 (66) | 94/153 (61) | 76/189 (40) | 60/154 (39) |
| Moderate dose | 90/178 (51) | 133/155 (86) | 119/177 (67) | 91/154 (59) | 75/178 (42) | 64/155 (41) | |
| High dose | 90/159 (57) | 131/162 (81) | 115/159 (72) | 100/161 (62) | 68/159 (43) | 69/162 (43) | |
| 9344 | No paclitaxel | 241/640 (38) | 331/871 (38) | 436/639 (68) | 544/866 (63) | 325/639 (51) | 484/871 (56) |
| Paclitaxel | 235/623 (38) | 356/901 (40) | 424/621 (68) | 555/893 (62) | 317/623 (51) | 502/900 (56) | |
| 9741 | Every 3 wk | 154/318 (48) | 291/569 (51) | 213/321 (66) | 334/565 (59) | 133/327 (41) | 225/575 (39) |
| Every 2 wk | 154/325 (47) | 305/571 (53) | 218/333 (65) | 314/579 (54) | 128/336 (38) | 235/585 (40) | |