Table 2.
Number needed to treat and benefit for 1000 patients
|
Diabetic patients
|
Non-diabetic patients
|
All patients
|
|||||||
|---|---|---|---|---|---|---|---|---|---|
| Outcome | NNT | Benefit/1000 | Weighted follow-up average (years) | NNT | Benefit/1000 | Weighted follow-up average (years) | NNT | Benefit/1000 | Weighted follow-up average (years) |
| Primary prevention | |||||||||
| Major coronary event | 37 (24 to 75) | 27 | 4.5 | 47 (35 to 73) | 21 | 4.3 | 44 (33 to 64) | 23 | 4.4 |
| Secondary prevention | |||||||||
| Major coronary event | 15 (11 to 24) | 67 | 5.1 | 17 (14 to 20) | 59 | 5.1 | 16 (14 to 19) | 63 | 5.1 |
| CHD death or non-fatal MI | 15 (9 to 40) | 67 | 5.0 | 21 (17 to 27) | 48 | 5.0 | 21 (17 to 26) | 48 | 5.0 |
| CHD death | 19 (10 to 90) | 53 | 5.0 | 61 (31 to 318) | 16 | 5.0 | 54 (36 to 90) | 19 | 5.0 |
| Non-fatal MI | 11 (5 to 141) | 91 | 5.0 | 34 (23 to 60) | 29 | 5.0 | 31 (21 to 56) | 32 | 5.0 |
| Revascularisation | 11 (8 to 21) | 91 | 5.6 | 25 (20 to 32) | 40 | 5.3 | 23 (18 to 29) | 43 | 5.3 |
| Stroke | 19 (11 to 50) | 53 | 5.5 | 84 (53 to 157) | 12 | 5.3 | 66 (47 to 106) | 15 | 5.3 |
CHD=coronary heart disease; MI=myocardial infarction; NNT=number needed to treat.