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. 2006 May;13(5):584–593. doi: 10.1128/CVI.13.5.584-593.2006

FIG. 2.

FIG. 2.

Relative release in vitro of ECP and EPX in whole blood cultures stimulated with SWA, SEA, or medium alone. The relative release is calculated as the released amount of ECP and EPX as a percentage of the total content of ECP or EPX extracted from whole blood before the cultures were set up. The boxes represent the 25th, 50th, and 75th percentile ranges, and the error bars illustrate the ranges of the 10th and 90th percentiles. Significant time-dependent release of ECP and EPX was seen in all cultures (P ≤ 2.2 × 10−15 for all). Optimal release of both ECP and EPX was seen in SEA-stimulated cultures from bleed B after 96 h of incubation. For optimal ECP release, the P values were 3.8 × 10−6 and 1.6 × 10−7 (*), respectively, compared to 96-h cultures stimulated with SWA or medium alone. For optimal EPX release, P values were 7.34 × 10−10 and 5.46 × 10−10 (§), compared to 96-h cultures from bleed B stimulated with SWA or medium alone. Levels of significance compared to SEA-stimulated 96-h cultures from bleed A and bleed C are indicated.