FIG. 1.

Categories of genes whose transcription is modulated by heat shock treatment. The data were organized according to a number of different categories suggested for the analysis of transcripts from protozoan parasites (http://www.ebi.ac.uk/parasites/_old/FalcipProteome/geneclass.html). Note that a homogenous color code (appearing in a clockwise representation) is associated with each category. The distribution of total genes was obtained by the percentages of different categories of genes carried on the microarray (these genes were basically randomly chosen after the sequencing of cDNA libraries). Of the genes up regulated by heat shock, 19% encode factors involved in cell rescue. Interestingly, 14% are related to pathogenesis, and very few correspond to hypothetical proteins. The class distribution of transcripts down regulated by heat shock more or less matches the distribution of genes represented on the microarray.