TABLE 1.
Inhibition of chlamydial infectivity in Swiss Webster mice by pretreatment of organisms with N-glycanase
Strain | Inhibition of chlamydial infectivity with (+) and without (−) glycanase treatment
|
|||||||
---|---|---|---|---|---|---|---|---|
Inhibition at 3 days p.i.
|
Inhibition at 7 days p.i.
|
|||||||
No. of mice positive/no. of mice tested
|
IFU/g of lung (% decrease)a
|
No. of mice positive/no. of mice tested
|
IFU/g of lung (% decrease)a
|
|||||
− | + | − | + | − | + | − | + | |
C. pneumoniae AR-39 | 6/6 | 0/6b | 2.8 × 105 | 0 (100) | 6/6 | 1/7b | 1.1 × 105 | 1.2 × 104 (91) |
C. trachomatis E/UW-5/Cx | 6/6 | 6/6 | 1.4 × 106 | 8.4 × 105b (40) | 6/6 | 6/6 | 9.9 × 103 | 1.0 × 103b (90) |
C. trachomatis L2/434/Bu | 6/6 | 6/6 | 1.1 × 106 | 4.6 × 102b (99) | 6/7 | 0/7 | 2.6 × 105 | 0 (100) |
Data are the mean titers in lung. Percent decrease is relative to the IFU/g of lung in the control.
P < 0.05.