FIG. 1.

Growth of H. pylori J99 and isogenic histidine kinase null mutants. H. pylori strains were grown in BB-FBS (pH 7.0) and were then inoculated into fresh BB-FBS (initial pH of 5.0 or 7.0). OD₆₀₀ measurements were taken at the indicated time points. Growth of wild-type strain J99 and the isogenic histidine kinase mutants (J99-244Km [A], J99-165Km [B], and J99-1364Km [C]) are shown. Colony counts of cultures were performed in parallel and were consistent with the OD₆₀₀ readings (data not shown). These graphs depict analyses of triplicate cultures from single experiments (means ± SDs). The results shown are representative of three separate experiments.