TABLE 1.
Distribution of cell types in the spleens of 129S6 and 129S6-Slc11a1tm1Mcg mice
| Strain | No. of days p.i.c | Total no. of cellsa | Total no. of stained cells/spleen (106)a
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CD3 | CD4 | CD8 | B220 | MAC | F4/80 | αβ | γδ | Gr1 | Pan-NK | |||
| 129S6 | 0 | 20.0 ± 0.0 | 7.1 ± 0.5 | 5.2 ± 0.2 | 1.8 ± 0.2 | 12.3 ± 0.7 | 1.2 ± 0.2 | 1.5 ± 0.8 | 6.6 ± 0.3 | 0.4 ± 0.1 | 1.5 ± 0.1 | 0.4 ± 0.1 |
| 129S6 | 10 | 170.0 ± 19.3 | 70.8 ± 10.0 | 46.1 ± 6.7 | 19.6 ± 3.0 | 59.1 ± 6.0 | 27.2 ± 3.9 | 20.9 ± 2.9 | 76.3 ± 10.8 | 37.1 ± 4.1 | 20.1 ± 3.0 | 10.4 ± 1.6 |
| 129S6 | 42 | 16.3 ± 1.8 | 7.5 ± 0.9 | 5.9 ± 1.4 | 1.7 ± 0.2 | 9.3 ± 1.0 | 1.2 ± 0.2 | 1.9 ± 0.3 | 7.8 ± 1.2 | 1.7 ± 0.4 | 2.1 ± 0.4 | 0.4 ± 0.1 |
| 129S6−/−b | 0 | 13.9 ± 6.1 | 5.1 ± 2.6 | 3.9 ± 2.2 | 1.2 ± 0.5 | 8.9 ± 3.3 | 0.6 ± 0.3 | 0.5 ± 0.2 | 4.4 ± 3.4 | 0.2 ± 0.1 | 0.8 ± 0.4 | 0.2 ± 0.1 |
| 129S6−/−b | 10 | 149.0 ± 22.5 | 53.7 ± 4.5 | 38.1 ± 3.3 | 14.4 ± 1.4 | 52.4 ± 8.3 | 22.5 ± 4.1 | 16.8 ± 3.4 | 60.2 ± 6.3 | 33.2 ± 6.7 | 18.5 ± 3.1 | 9.4 ± 1.8 |
| 129S6−/−b | 42 | 17.3 ± 2.7 | 6.7 ± 1.2 | 4.9 ± 4.7 | 1.8 ± 0.3 | 8.9 ± 1.6 | 1.8 ± 0.7 | 1.3 ± 0.2 | 7.4 ± 1.2 | 1.1 ± 0.2 | 2.7 ± 0.7 | 0.3 ± 0.0 |
a
Data are represented as the mean ± the standard error of the mean.
b
Slc11a1tm1Mcg knockout mice.
c
Data were obtained from averages of two, four, and six mice at days 0, 10, and 42 postinfection (p.i.), respectively.