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Selection experiments using mixtures of OpaI and Opa− variants of FA1090CmR and wild-type FA1090 (Cms)
| Expt with indicated inoculuma | No. of mice with selection of preexisting OpaI population/total (%) |
|---|---|
| OpaI Cmr:Opa− Cms | |
| 1 | 5/6 (83) |
| 2 | 3/5 (60) |
| 3 | 4/5 (80) |
| OpaI Cms:Opa− Cmr | |
| 4 | 0/7 (0) |
| 5 | 1/8 (13) |
| 6 | 3/5 (60) |
OpaI Cmr:Opa− Cms inocula contained 8 to 18% OpaI Cmr and 72 to 79% Opa− Cms variants. OpaI Cms:Opa− Cmr inocula contained 5 to 24% OpaI Cms and 17 to 74% Opa− Cmr variants.
