TABLE 1.
Heterologous strain in mixed challenge infectiona | Test(s)b for immunizing strain:
|
|||
---|---|---|---|---|
AS | AJ | AQ | CB | |
AS | EE | EE | RTQ-PCR, EE | |
AJ | NT | RTQ-PCR | RTQ-PCR | |
AQ | NT | RTQ-PCR | NT | |
CB | RTQ-PCR, EE | RTQ-PCR, EE | EE |
Combinations of genetically distinct cloned lines of P. c. chabaudi which have been tested for evidence of strain-specific immunity in mixed infections of two strains, one of which is the same as (homologous) and the other different from (heterologous) the strain used to induce immunity in female CBA mice.
Differential elimination of homologous (immunizing) strain from mixed challenge infection in strain-specifically-immunized mice, as measured by RTQ-PCR or by enzyme electrophoresis (EE). NT, combination not tested.