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Protective activity of P1.16 PorA-specific hIgG1 to hIgG4 isotypes in complement-sufficient HsdBrlHan:WIST infant rats. The results are given as GM bacteremia level (CFU per milliliter of blood) in each group of five or six animals. Error bars indicate upper 95% confidence levels. The different isotypes were tested in separate experiments. *, P < 0.05 compared to control animals not given antibody, LSD. **, P value obtained with one-way ANOVA.
