TABLE 1.
Strain |
H. ducreyi CFU per lesion biopsya at day p.i.:
|
% H. ducreyi-positive biopsiesb at day p.i.:
|
||
---|---|---|---|---|
2 | 7 | 2 | 7 | |
35000HP | 161.0 (90.5-497.4) | 146.8 (111.2-320.8) | 60.3 (30.9-75.7) | 72.9 (57.5-96.8) |
35000HPncaA | 30.4 (19.5-82.3)c | 6.1 (2.2-28.6)c | 56.4 (31.6-68.7) | 20.0 (17.1-61.7)c |
35000HPncaA merodiploid | 280.9 (181.0-1390.2) | 320.3 (148.3-1080.7) | 70.0 (24.9-85.4) | 75.0 (64.3-95.7) |
Values indicate the observed mean CFU per biopsy, with 95% confidence intervals in parentheses, as modeled by poisson regression and GEE adjustment to account for variability between pigs.
Values indicate the observed mean proportion of biopsies harboring viable H. ducreyi, with 95% confidence intervals in parentheses, as modeled by logistic regression and GEE adjustment.
Significantly different (P < 0.0001) from values for wild-type or merodiploid lesions on same day postinoculation.