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Quantitative RT-PCR in Nox4 siRNA stable 786-0 clones. A. 786-0 PRC, lacking functional VHL product, and B. 786-0 WT VHL-expressing cells demonstrate decreased relative expression of HIF2-α and HIF transcription targets VEGF, Glut-1 and TGF-α and VHL with no significant change in Lamin expression. Error bars represent mean +/- standard error. Asterisks: p < 0.005.
