Skip to main content
. Author manuscript; available in PMC: 2006 Oct 1.
Published in final edited form as: Am J Physiol Renal Physiol. 2005 Oct;289(4):F816–F825. doi: 10.1152/ajprenal.00024.2005

Fig. 3.

Fig. 3.

Inhibition of TGF-β type I receptor/ALK5 kinase, but not p38 kinase, blocks F-actin assembly by TGF-β. HUVEC were treated with TGF-β1 (10 ng/ml) for 30 min alone or preincubated with inhibitors for the TGF-β type I receptor kinase (SB-505124, 500 nM) or p38 kinase inhibitor (SB-203580, 5 μM) and imaged by confocal analysis (A). F/G actin quantitation was performed using a fluorescent plate reader (B). There were 6 replicates per condition and 3 separate experiments were performed. Data are presented as the mean F/G actin ratio ± SE from a representative experiment. *P < 0.05 vs. control.