Table 2.
entry | L | alkyne | R | R′ | 10:11 | yield (%) |
---|---|---|---|---|---|---|
1 | Py | 9a | Ph | CH3 | 15:1 | 64 |
2 | Py | 9b | pCF3Ph | CH3 | >20:1 | NA |
3 | Py | 9c | pMeOPh | CH3 | 1:2 | NA |
4 | Lut | 9a | Ph | CH3 | 1.2:1 | 51 |
5 | Me2S | 9a | Ph | CH3 | 30:1 | 46 |
6 | Py | 9d | Ph | C2H5 | 10:1 | 66 |
7 | Py | 9e | C3H7 | C3H7 | 63 | |
8 | Py | 9f | CH3 | C5H11 | 1.5:1 | 61 |
9 | Py | 9g | CH3 | cC6H11 | 3:1 | 64 |