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. 2001 Jan 9;98(2):441–444. doi: 10.1073/pnas.021555498

Figure 2.

Figure 2

Rpp20 has strong homology with ABC transporter ATPases (in particular a putative ABC transporter ATPase from A. thaliana, see below), and weak homology with a Upf1p subfamily of the DEAD-box ATP-dependent RNA helicase superfamily. (A) Schematic representation of the common motifs of Rpp20, the Upf1p subfamily, and ABC transporters. The alignment of sequence conservation of ABC transporter ATPase super family is described in ref. 12, and that of the Upf1p family is reviewed in refs. 6 and 7. Fully conserved residues are shown in uppercase, semiconserved in lowercase, and nonconserved are designated as x. (B) Sequence alignment of Rpp20 and the C-terminal fragment (starting at residue 163) of the ABC transporter ATPase from A. thaliana. Identical residues are marked by an asterisk; residues of high similarity by a colon; and residues of low similarity by a period. Gaps are shown as dashed lines.