TABLE 1.

Genetic and phenotypic evidence suggesting that ad450sd is a gain-of-function egl-4 allele

	ad450sd	egl-4 (lof)
Genetics	Semidominanta	Recessiveb
Genetic map location	Between ced-2 and lin-1a	Between ced-2 and lin-1b
Longevity	Decreasedc	Increasedd
Retained eggs	Decreasede	Increasedbef
Body size	Decreasede	Increaseddefg
Locomotion in the presence of food	Decreasede	Increasedg
Intestinal darkness	Decreasede	Increaseddef
Nile red staining	Increasede	Decreasede
Dauer formation	Decreasede	Increasedf

lof, loss of function.

^aAvery (1993).

^bTrent et al. (1983).

^cLakowski and Hekimi (1998).

^dHirose et al. (2003).

^eThis work.

^fDaniels et al. (2000).

^gFujiwara et al. (2002).