TABLE 1.

Mechanisms that cause new inversions to spread

Mechanism	Fate of inversion
Indirect effects: recombination suppression
Local adaptation	Near fixation
Epistatic selection	Fixation
Deleterious mutation	Neutral polymorphism
Drift acting on an underdominant inversion	Fixation or loss
Direct positive effects of the chromosomal lesion
Effects of breakpoints	Fixation or stable polymorphism
Position effects	Fixation or stable polymorphism
Meiotic drive	Fixation or stable polymorphism
Hitchhiking with a spreading advantageous mutation	Neutral polymorphism