Figure 4. Conformational features of Ara h 2 and Ara h 6.

(A) Secondary-structure elements of rAra h 6 (Asp¹²–Glu³⁹; Ser⁵⁰–Asp¹¹⁸) based on the lowest energy structure. Disulphide bonds are indicated in yellow. The proteolytically digested protein consists of two subunits connected by disulphide bonds, H1 and H2, H3, H4 and H5. The Figure was generated using VMD [50]. (B) Secondary-structure elements of an Ara h 2 model structure based on the experimental structure of prAra h 6. The Figure was generated using MOLMOL [49] (C) Superposition of the helical regions of Ara h 6 (red) with RicC3 (blue) and SFA-8 (green) [26,27]. The Figure was generated using MOLMOL [49].