Table 2. tubA is not a substrate for key CYPs.
| IC50 (μM) | ||||
|---|---|---|---|---|
| Compound | Enzyme… | CYP1A2 | CYP2D6 | CYP3A4 |
| tubA | >100 | >100 | 82 | |
| Paclitaxel | >100 | >100 | >100 | |
| Vinblastine | >100 | >100 | >100 | |
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