Table 1. Frequency of recombination between intragenic repeats in selected DNA repair and recombination mutants.

The frequency of recombination in the intragenic repeats in FLO1 was determined by measuring the frequency of Ura⁻ segregants (see Methods). The frequency measured in various DNA recombination and repair mutants was compared to that of an otherwise isogenic Rad⁺ strain (KV133). The recombination frequency in strain KV133 is 1 ×10⁻⁵ (see Fig. 3c). Values marked with an * indicate significant differences from the Rad⁺ control as measured by the student t-test at a 99% confidence level. All measurements were repeated at least three times.

Relevant Genotype	Ratio compared to WT
FLO1::URA3 (WT)	1
FLO1::URA3 Δrad1	0.7
FLO1::URA3 Δrad27	37*
FLO1::URA3 Δrad50	0.09*
FLO1::URA3 Δrad51	0.94
FLO1::URA3 Δrad52	0.05*
FLO1::URA3 Δrad59	0.24*
FLO1::URA3 Δrad1 Δrad52	0.01*
FLO1::URA3 Δdnl4	0.9
URA3 inserted at URA3 locus	< 0.03*