Skip to main content
. Author manuscript; available in PMC: 2007 Feb 1.
Published in final edited form as: Eur J Neurosci. 2006 Feb;23(4):984–994. doi: 10.1111/j.1460-9568.2006.04621.x

Fig. 6.

Fig. 6

Effects of opioid receptor antagonists on i.c.v. administered (+)BW373U86 (100 nmol), leu-enkephalin (100 nmol) and met-enkephalin (100 nmol) induced increases in BDNF mRNA expression in rats. Each value represents the mean percent of (veh + veh) ± SEM (n = 4–6). Levels of BDNF mRNA expression were determined 3 h after agonist administration. Subcutaneous administration of sterile water (Veh, 1 mL/kg), naltrindole (NTI, 1 mg/kg) or naltrexone (NTX, 0.1 mg/kg) was conducted 15 min before agonist administration. *P < 0.05 and **P < 0.01 compared with the veh + veh group; #P < 0.05 and ##P < 0.01 compared with the veh + agonist group.