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(C) Sequence alignment of TYW4 with its homologs. The conserved domain, LCM, is indicated by a line. The boxed regions are Ado-Met-binding motifs, including motif I–III and post-I. The residues important for protein carboxyl methyltransferase activity are indicated by arrowheads. The C-terminal region of TYW4 is shaded. (D) Domain structure of the plant TYW3-4C-2 protein. The plant TYW3-4C-2 protein is a large fusion protein composed of TYW3, the CTD of TYW4 and TYW2.
