Figure 3.

The RAMPs. (A) The conserved motifs of the RAMP superfamily and individual RAMP families. h designates a hydrophobic residue, p designates a polar residues, t designates a residue with high turn-forming propensity, and + designates a positively charged residue. (B) A ribbon model of the structure of a RAMP protein from Thermus thermophilus (PDB entry 1wj9). Two ferredoxin-like domains are rainbow-colored from N- to C-terminus such that the corresponding strands in the two each domain receive the same color. The G-rich conserved loop in the C-terminal domain is colored black, structurally disordered regions are shown by dots, α-helices and β-strands are numbered consecutively throughout the sequence from α1 to α4 and from β1 to β8.