Table 2.
Distribution of genotypes in controls without atrial fibrillation (AF) and subjects with AF.
| Locus | AF Controls (n = 97) | AF Cases (n = 97) | P value (Chi-square) OR (95%CI)* |
| ACE gene I/D | 0.44 | ||
| II | 22.7% | 31.1% | 0.65 (0.33–1.27) |
| ID | 50.0% | 43.3% | 0.92 (0.47–1.78) |
| DD | 27.3% | 25.6% | |
| AGT gene G-6A | 0.96 | ||
| AA | 16.1% | 17.6% | 1.07 (0.59–1.97) |
| AG | 46.0% | 46.2% | 1.11 (0.51–2.44) |
| GG | 37.9% | 36.3% | |
| AT1R gene A1166C | 0.28 | ||
| CC | 8.0% | 11.6% | 0.73 (0.41–1.32) |
| AC | 46.0% | 34.7% | 1.50 (0.55–4.05) |
| AA | 46.0% | 53.7% | |
| Bradykinin 2 C58T CC | 34.1% | 36.8% | 0.92 0.89 (0.48–1.63) |
| TT | 18.2% | 16.8% | 0.91 (0.43–1.96) |
| CT | 47.7% | 46.3% | |
| Bradykinin 2 C181T | 0.54 | ||
| CC | 72.7% | 76.3% | 0.83 (0.42–1.62) |
| TT | 1.1% | n.a. (empty cells) | |
| CT | 26.1% | 23.7% | |
| Bradykinin 2 exon1 | 0.35 | ||
| -9/-9 | 38.2% | 29.3% | 1.08 (0.60–1.94) |
| -9/+9 | 43.8% | 45.7% | 1.49 (0.80–2.77) |
| +9/+9 | 18.0% | 25.0% | 1.52 (0.74–3.12) |
| CETP I405V | 0.02 | ||
| AA | 44.3% | 46.8% | 0.90 (0.50–1.62) |
| AG | 52.3% | 38.3% | 4.96 (1.37–17.90) |
| GG | 3.4% | 14.9% | |
| CETP TaqIB | 0.02 | ||
| B1B1 | 24.1% | 44.1% | 0.40 (0.21–0.77) |
| B1B2 | 62.1% | 43.0% | 0.93 (0.39–2.19) |
| B2B2 | 13.8% | 12.9% |
* Odds ratios (95% Confidence Intervals) for the presence of AF on the electrocardiogram were obtained by logistic regression; the top OR is for autosomal dominant model and the bottom for autosomal recessive model.