Table 1.

Results of Guthrie cards screening in patients with ALL

Patient	Molecular marker	Detection sensitivity	% blasts at diagnosis	Age at diagnosis	Guthrie card
ALL1	Vd2	10-4	N.A.	2 y 8 mo	negative
	VH3	10-5			negative
ALL2	VH3	10-4	50%	3 y 3 mo	negative
	TEL/AML1	10-4-10-5			negative
ALL3	VgI	10-5	>55%	4 y 5 mo	positive
	VkIA	10-4			negative
ALL4	Vd2	10-5	N.A.	3 y 6 mo	positive
	VH3	10-4			positive
ALL5	VH3	10-5	70%	4 y	negative
ALL6	VH3	10-4	84%	1 y 8 mo	negative
	VH1	10-5			negative
ALL7	VH1	10-5	83%	3 y 3 mo	negative
ALL8	VH3	10-4	79%	2 y 6 mo	negative
ALL9	VH3	10-4	89%	2 y 3 mo	negative
	VH4	10-5			negative
ALL10	VgI	10-4	>30%	3 y 9 mo	negative
ALL11	TEL/AML1	10-4-10-5	80%	5 y 7 mo	negative
ALL12	TEL/AML1	10-5	77%	3 y 6 mo	positive