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. 2006 May 19;2(5):e74. doi: 10.1371/journal.pgen.0020074

Figure 3. Identification of Genes Required for Robust RNAi.

Figure 3

WT (N2) young adult hermaphrodites were co-injected with 300 ng/μl of each candidate dsRNA and 75 ng/μl of mom-2 dsRNA. rde-1(RNAi) was used as a positive control, while unc-15(RNAi), unc-22(RNAi), and lin-1(RNAi) were used as negative controls. The horizontal line indicates the cut-off for viability (>30%) that was used to define the positive genes reported in Table 3. All positive genes displayed significant differences from the negative controls with p < 0.01 (t test). The positive candidates include three genes (gfl-1, mes-4, and zfp-1) that were previously identified by Dudley et al. using the same approach [50]. Error bars represent standard error.