Table 1.

RCTs for the Treatment of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)^*

					Symptom Outcomes†			Effect
Study (Year)	Medication	N	Mean age	Duration in weeks	Pain	Urinary Symptoms	Quality of Life	Any	Overall (NNT)
Alpha-blockers, selective
Mehik et al., (2003)14	Alfuzosin	70	49	24	+	−	−	+	2
Cheah et al., (2003)15	Terazosin	100	35	14	+	+	+	+	5
Alpha-blocker, subtype-1A-Selective
Nickel et al., (2004)16	Tamsulosin	58	41	6	+	+	+	+	6
Alexander et al., (2004)17	Tamsulosin	196	45	6	−	−	−	−	20
5-alpha reductase inhibitors
Nickel et al., (2004)18	Finasteride	76	47	24	−	−	−	−	7
Antibiotics
Alexander et al., (2004)17	Ciprofloxacin	196	45	6	−	−	−	−	20
Nickel et al., (2003)19	Levofloxacin	80	56	6	−	−	−	−	53
Miscellaneous
De Rose et al., (2004)20	Mepartricin	36	33	8	+	−	+	+	N/A‡
Nickel et al., (2005)21	Pentosan polysulfate	100	38	16	−	−	+	+	6
Nickel et al., (2003)22	Rofecoxib	161	48	6	+	+	+	+	5
Complementary and Alternative Medications
Wang et al., (2004)23	Chuanshenton g	38	NR	1	+	+	+	+	3
Lu et al., (2004)24	Flavoxate	45	NR	4	+	+	+	+	N/A‡
Shoskes et al., (1999)25	Quercetin	30	45	4	+	−	+	+	3

^*Abbreviations: NR – not reported,

^†+ means outcome significantly better than in control group, − means not significantly better,

^‡N/A – not applicable, data for NNT calculation not provided