Skip to main content
. 2000 Dec 19;98(2):591–596. doi: 10.1073/pnas.011528698

Figure 3.

Figure 3

Summary of methylation and imprinting status of 37 patients whose tumors were microsatellite stable [MSI(−)] but had no germline mutation of MLH1 or MSH2, 20 patients whose tumors were microsatellite unstable [MSI(+)] but had no germline mutation of MLH1 or MSH2[Mut(−)], and five patients with MSI(+) tumors and a germline mutation of MLH1[Mut(+)]. Shown is the methylation status of the promoters of MLH1 and p16 in the tumors (black, methylated; white, unmethylated) and imprinting status (black, loss of imprinting; white, retention of imprinting) in tumors and corresponding normal colonic mucosa (NM). Case identifiers are in the left column. MLH1-1, promoter region described by Herman et al. (2). MLH1-2, promoter region described by Deng et al. (22).