Figure 2.

Inhibition of polκ polymerase activity by RNA aptamers. Primer extension reactions containing 8 nM truncated polκ and 300 nM 5′-³²P-labeled primer-template were performed in the presence of 240 nM of each aptamer as indicated. Reactions were then quenched and products were analyzed by denaturing PAGE. In the left most lane (−), the reaction contained no aptamer.