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. 2005 Sep 8;568(Pt 3):905–915. doi: 10.1113/jphysiol.2005.094003

Figure 7. Ultrastructural identification of exocytic and endocytic vesicles in PC12 cells.

Figure 7

Images were obtained at the base of the cells perpendicular to glass coverslips (black arrows). The surface of the glass appeared irregular due to deformation by tissue processing. A, a control cell without stimulation and photoconversion. B–E, cells immersed in FM1-43 for 20 s and stimulated by photolysis of NPE 10 s after the initial exposure to the tracer and fixed 10 s after photolysis. Photoconversion of DAB was induced by FM1-43 molecules remaining after tracer washout. LV and SEx indicate a single LV before and after exocytosis, respectively. CEx represents compound exocytosis by LVs. En denotes direct endocytic vesicles. The external scale bar (0.5 μm) in B applies to all panels.