Figure 10. Ryanodine does not affect Ca²⁺ transients seen in response to single action potentials.

Action-potential-evoked Ca²⁺ responses were measured in control (A) and in the presence of 20 μm ryanodine (B). Measurement of the amplitude of the Ca²⁺ response evoked by a single action potential at two discrete locations along the axon (regions 1 and 2) showed no significant difference between the control responses and those recorded in ryanodine (C and D).