A, typical examples of the effects of the intravenous administration of C6 (10 mg kg−1) and Atr (100 μg kg−1) on the MBF increases evoked by TG stimulation (•) for 20 s with 20 V at 20 Hz using 2 ms pulses. B, the MBF increases evoked by TG stimulation 10, 30 and 60 min after administration of C6 (white bars, n = 4 in each group) and Atr (black bars, n = 3 in each group) are expressed as a percentage of the pretreatment response and given as means ± s.e.m. The statistical significance of the differences in this pretreatment response (control) was assessed by ANOVA followed by a post hoc test (Fisher's PLSD) (*P < 0.05, **P < 0.01, ***P < 0.001).