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A, ΔR-CFTR single-channel current traces in the presence of 2.75 mm ATP, 30 μm P-ATP and 0.1 μm P-ATP. B, open probability (Po) dose–response relationships of P-ATP (•) and that of ATP (○; from Bompadre et al. 2005a). Continuous lines are Hill equation fits to the data. The n values for the fits are 1.05 ± 0.30 for P-ATP and 0.66 ± 0.23 for ATP.
