Figure 8. CP99994 and SB223412 reduce peak expiratory pressures during cough initiated from the tracheal or laryngeal mucosa.

Data are presented as the mean ± s.e.m. expiratory pressure during cough relative to peak tidal expiratory pressures. All animals were challenged with 3 μm capsaicin administered to the tracheal perfusate. At least one cough evoked electrically (A) or mechanically (B) in each of 5 animals in each treatment group was analysed.