Figure 6. Relationship between initial rate of change of glomerular volume per unit initial glomerular volume and oncotic gradient applied.

Populations of glomeruli were exposed to different oncotic gradients, by altering the BSA concentration of the ‘concentrated’ perifusate. As predicted by Starling's equation, the magnitude of the rate of change of initial glomerular volume per unit initial glomerular volume was linearly related to the magnitude of the oncotic gradient applied. (Linear regression (ΔV/Δt)/V_i= 0.02 mmHg + 0.1 s⁻¹; r = 0.59, n = 28, P < 0.001).