. 2005 Oct 20;570(Pt 1):185–205. doi: 10.1113/jphysiol.2005.094615

Table 4.

Forearm muscle lactate efflux, V̇_O₂, V̇_CO₂ and RER at rest, immediately post-fatigue and during recovery, under Con and Alk conditions

	Rest	Fatigue	Recovery (min)

			+1	+2	+5	+10
Con
Lac⁻_m efflux	−0.2 ± 0.6	−182.3 ± 50.8^*	−134.8 ± 36.4^*	−88.0 ± 24.8^*	−46.8 ± 14.2^*	−18.3 ± 6.2^*
V̇_m,O2	0.6 ± 0.1	22.2 ± 4.0^*	4.5 ± 0.5	1.8 ± 0.2	1.3 ± 0.1	1.0 ± 0.1
V̇_m,CO₂	0.5 ± 0.2	17.7 ± 7.3^*	4.9 ± 1.5	1.1 ± 0.3	0.8 ± 0.2	1.0 ± 0.3
RER_m	0.71 ± 0.2	0.98 ± 0.06^*	0.86 ± 0.19^*	0.59 ± 0.08^*	0.56 ± 0.09^*	0.56 ± 0.25^*
Alk
Lac⁻_m efflux^‡	−1.0 ± 1.4	−353.7 ± 110.4^*	−159.0 ± 45.9^*	−144.9 ± 52.7^*	−57.6 ± 21.0^*	−24.8 ± 11.6^*
V̇_m,O₂	0.6 ± 0.1	20.4 ± 4.1^*	4.4 ± 1.1	2.1 ± 0.5	1.1 ± 0.2	1.0 ± 0.2
V̇_m,CO₂	1.6 ± 0.9	18.1 ± 4.3^*	9.9 ± 3.2	7.7 ± 3.3	4.8 ± 2.1	3.8 ± 1.3
RER_m	0.94 ± 0.2	0.90 ± 0.08^*	0.92 ± 0.17^*	0.70 ± 0.57^*	0.60 ± 0.46^*	0.54 ± 0.08^*

Net Lac⁻ flux expressed in µmol min⁻¹ and V̇_O₂, in ml min⁻¹. Mean ± s.e.m., n = 6;

Different from rest (P < 0.001).

^‡

Alk > Con during recovery (P < 0.05). A negative value denotes net efflux from contracting musculature, and positive values denote net influx. Muscle lactate efflux calculated from ([BLac⁻]_a-v× forearm blood flow), with [BLac⁻]_a-v corrected for arterio-venous ΔBV.