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. 2005 Oct 20;570(Pt 1):169–183. doi: 10.1113/jphysiol.2005.096073

Figure 6. Responses of a single anterior cingulate cortex (ACC) neurone to 13 trials of 50 mmHg colorectal distension (CRD) repeated at 5-min intervals.

Figure 6

Neuronal responses to colorectal distension remained consistently excitatory. Spontaneous activity more than doubled after the 10th trial at 45 min, which suggests that sensitization occurred.