Virus replication during the “macrophage phase” of
SHIVDH12R infection. Rhesus macaque Rh H27 was infected
with SHIVDH12R (4.1 × 105
TCID50) and killed at week 12.6. Specimens from mesenteric
lymph node (a), ileum (b), spleen
(c), liver (d), and kidney
(e) were evaluated for virus replication by ISH.
(Original magnifications: a, ×10; Inset,
×30; b, ×10; c, ×20; d,
×20; and e, ×10.)