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. 2005 Feb 17;564(Pt 2):603–617. doi: 10.1113/jphysiol.2005.083238

Figure 2. Effects of RGD peptide on force development.

Figure 2

A, representative graph of force versus frequency relationship. B, acute effect of 1 mm RGD peptide on the active force generated by papillary muscle from the right ventricle of a mouse heart. A significant inhibition of force is observed. C, effect of varying concentrations of RGD on force development. Note that 1 mm GRGDNP peptide causes maximal inhibition of force development. The 100% value of force/cross-sectional area represents the control measurement prior to addition of the RGD peptide. Data are presented as mean ± s.e.m., *P < 0.05, paired t test.