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. 2005 Feb 17;564(Pt 2):603–617. doi: 10.1113/jphysiol.2005.083238

Figure 4. Effects of native, denatured and digested fragments of collagen on force development.

Figure 4

A, 7.5%PAGE analysis of collagen samples under non-denaturing and non-reducing conditions. NC, native collagen; DEN, denatured collagen; DIGEST, collagen digested with human neutrophil elastase enzyme. B, effect of native type 1 collagen versus denatured and digested fragments of collagen on papillary muscle force development. Denatured and digested fragments of collagen significantly inhibit the force production. Data are presented as mean ± s.e.m., *P < 0.05 (ANOVA with Duncan's multiple range test).