Figure 1. OEA excites capsaicin-sensitive vagal sensory neurones.
A, example of nodose ganglion neurone under patch clamp; scale, 20 μm. B, response of a current-clamped neurone to 10 μm OEA and 250 nm capsaicin. C, responses of capsaicin-insensitive (left) and capsaicin-sensitive (right) neurones to 10 μm OEA and 250 nm capsaicin. Cells were voltage clamped at −60 mV. D, mean current evoked by 10 μm OEA and 250 nm capsaicin in six neurones. E, capsaicin- and OEA-evoked currents exhibit similar tachyphylaxis.