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. 2005 Feb 24;564(Pt 2):465–474. doi: 10.1113/jphysiol.2005.084012

Figure 4. GABAA receptor agonist potencies and effects of antagonists are independent of postnatal age.

Figure 4

A, concentration–response curves obtained for the GABA agonists, muscimol (circles) and taurine (squares), on dissociated ICG neurones for P2–5 (filled symbols) and P45–49 (open symbols) groups. n = 5 cells for each agonist and age group. B, effect of the GABAA receptor-channel antagonists, bicuculline (Bic) and picrotoxin (PicTx), and modulators on GABA- (Bi) and taurine- (Bii) evoked currents (10 μm GABA for Bic, DMCM, Zn2+; 100 μm GABA for PicTx and TPMPA; 50 mm taurine) recorded from dissociated ICG neurones of different postnatal age. n = 4–8 cells per GABA receptor antagonist/modulator and age group. Holding potential, −60 mV for both A and B.