Figure 3. Spontaneous synaptic activity in Purkinje cell at P0.
A, fast inward current recorded in a Purkinje cell at a holding potential of −70 mV when stepped to 0 mV. B, the spontaneous activity recorded in a Purkinje cell at a holding potential of −70 mV (top traces; 96 EPSCs recorded over a 180 s control period) is completely abolished by bath application of CNQX (bottom traces; no EPSCs recorded over a 300-s period of CNQX application). C, 1 and 2, examples of two spontaneous EPSCs observed in A at a larger time scale. 3, averaged trace for the same cell.