Table 1.
Simple correlations among measures maternal placental (caruncular) and fetal placental (cotyledonary) angiogenesis and expression of mRNA for angiogenic factors throughout the last two-thirds of gestation in sheep
| Maternal caruncle | Fetal cotyledon | |||||
|---|---|---|---|---|---|---|
| Angiogenic factor | Capillary area density (%) | Capillary number density (no. per unit tissue) | Capillary surface density (mm mm−2) | Capillary area density (%) | Capillary number density (no. per unit tissue) | Capillary surface density (mm mm−2) |
| VEGF | 0.24 | −0.05 | −0.14 | 0.46 | 0.52 | 0.45 |
| P = 0.19 | P = 0.80 | P = 0.45 | P < 0.01 | P < 0.01 | P < 0.01 | |
| VEGFR-1 | 0.54 | 0.11 | 0.28 | 0.36 | 0.31 | 0.42 |
| P < 0.01 | P = 0.55 | P = 0.12 | P < 0.04 | P = 0.08 | P < 0.01 | |
| VEGFR-2 | 0.24 | −0.14 | −0.01 | −0.11 | −0.19 | −0.07 |
| P = 0.18 | P = 0.44 | P = 0.97 | P = 0.52 | P = 0.29 | P = 0.71 | |
| bFGF | −0.11 | −0.19 | −0.22 | 0.37 | 0.34 | 0.52 |
| P = 0.53 | P = 0.30 | P = 0.22 | P < 0.03 | P = 0.06 | P < 0.01 | |
| ANG-1 | 0.24 | 0.05 | −0.01 | 0.33 | 0.32 | 0.37 |
| P = 0.16 | P = 0.79 | P = 0.95 | P = 0.06 | P = 0.07 | P < 0.04 | |
| ANG-2 | 0.50 | 0.02 | 0.17 | 0.54 | 0.45 | 0.60 |
| P < 0.01 | P = 0.89 | P = 0.33 | P < 0.01 | P < 0.01 | P < 0.01 | |
| TIE-2 | 0.08 | −0.30 | −0.14 | 0.07 | −0.01 | 0.09 |
| P = 0.65 | P = 0.09 | P = 0.42 | P = 0.70 | P = 0.98 | P = 0.63 | |
Taken from Borowicz et al. (2004a,b), and unpublished observations (n = 4 ewes per day). Values represent Pearson correlation coefficients and probability levels. Significant correlations are shown in bold.