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. 2005 Mar 10;565(Pt 1):43–58. doi: 10.1113/jphysiol.2004.081745

Table 2.

Angiogenic factor mRNA expression in the maternal (caruncular) and fetal (cotyledonary) portion of the placentomes

Caruncular (n = 6) Cotyledon (n = 6)


Gene of interest Control Selenium Control Selenium
VEGF 0.73 ± 0.16 0.74 ± 0.09 1.92 ± 0.22 2.79 ± 0.54
VEGFR-1 1.34 ± 0.32 1.53 ± 0.23 3.40 ± 0.28 4.65 ± 0.84**
VEGFR-2 0.62 ± 0.05 0.87 ± 0.13 1.73 ± 0.22 1.73 ± 0.23
bFGF 4.91 ± 1.00 5.93 ± 0.76 2.80 ± 0.64 2.58 ± 0.36
FGF-R 1.91 ± 0.34 1.94 ± 0.36 4.33 ± 0.30 4.98 ± 0.67
ANG-1 0.56 ± 0.13 0.63 ± 0.07 1.72 ± 0.30 1.94 ± 0.27
ANG-2 0.87 ± 0.19 1.07 ± 0.12 2.24 ± 0.41 2.65 ± 0.48
TIE-2 1.24 ± 0.16 1.74 ± 0.31 2.51 ± 0.36 2.63 ± 0.20

Data are for ewes fed Control diets and ewes fed diets containing 3 p.p.m. Se from high-Se wheat, and are expressed relative to the 18S ribosomal mRNA level; significant differences between Control and Selenium are shown in bold.

**

Means ± standard error of the mean within a tissue and differ, P < 0.09.

Means ± standard error of the mean within a tissue and differ, P < 0.05.