Figure 6. Kinetics of slow inactivation were not altered in T323M and F1705I channels.
A, the time course of entry to slow inactivation at −10 mV was indistinguishable between WT (▪), T323M (○) and F1705I (▵). B, recovery from slow inactivation was monitored after a 30-s conditioning pulse at 0 mV, by applying very brief −10-mV test depolarizations during recovery at −120 mV (inset). Neither T323M (○) nor F1705I (▵) channels showed any alteration in recovery from slow inactivation compared to WT (▪) channels.