Figure 1. Maurocalcine (MCa) does not affect the depolarization-induced Ca2+ release in cultured myotubes.
A, confocal images of myotubes after 3 days in culture. Left, transmitted light image (differential interference contrast). Right, Fluo-4 fluorescence images acquired before (control) and at the indicated times after the addition of 140 mm KCl. B, changes in Fluo-4 fluorescence induced by depolarization (140 mm KCl) before (left) or after (right) application of 100 nm MCa. C, pooled data of the peak of the fluorescence change induced by depolarization before or 10 min after application of 100 nm MCa.