Table 3.

Biochemical parameters of skeletal muscles of CK mice

	WT		CK−/−
	Sedentary	Active	Sedentary	Active	CK effect	Activity effect	Interaction
Soleus
AK	408 ± 22	394 ± 21	467 ± 27	473 ± 49	ns	ns	ns
CK	1082 ± 91	1017 ± 47	nd	nd	***	ns	ns
mitochondrial CK	34 ± 4	61 ± 13	nd	nd	***	ns	ns
MM-CK	1048 ± 89	956 ± 45	nd	nd	***	ns	ns
LDH	122 ± 10	107 ± 13	110 ± 12	107 ± 18	ns	ns	ns
H-LDH subunit	122 ± 3	107 ± 12	110 ± 12	122 ± 12	ns	ns	ns
LDH H/M	0.99 ± 0.04	1.11 ± 0.12	1.42 ± 0.10*	1.21 ± 0.08	*	ns	ns
Gastrocnemius
AK	699 ± 104	599 ± 76	1299 ± 98**	1570 ± 119***	***	ns	ns
CK	2443 ± 202	2618 ± 252	nd	nd	***	ns	ns
Mitochondrial CK	2 ± 2	13 ± 8	nd	nd	***	ns	ns
MM-CK	2641 ± 228	2605 ± 246	nd	nd	***	ns	ns
LDH	336 ± 18	262 ± 47	370 ± 51	369 ± 30	ns	ns	ns
H-LDH subunit	11 ± 2	10 ± 4	36 ± 9**	45 ± 6**	***	ns	ns
LDH H/M	0.02 ± 0.01	0.04 ± 0.01	0.11 ± 0.03**	0.14 ± 0.02**	***	ns	ns

Values are means in IU (g wet weight)⁻¹ ± s.e.m. nd, not detectable; ns, not significant; CK, creatine kinase; LDH, lactate dehydrogenase; AK, adenylate kinase. *P < 0.05; **P < 0.01; ***P < 0.001. *deficient versus control. H-LDH, see Methods for calculation.